The paper ¨Microglia-Secreted Galectin-3 Acts as a Toll-like
Receptor 4 Ligand and Contributes to Microglial
Activation¨is published by professors Hakon Leffler and
Tomas Deierborg in Cell Reports.
November 12, 2014
The paper ¨The role of Galectin-3 in α-synuclein-induced
microglial activation¨ is published by Dr. Antonio
Boza-Serrano and professors Tomas Deierborg, Hakon Leffler
and Ulf Nilsson in Acta Neuropath. Commun.
October 31, 2014
The paper ¨Gal-3 regulates the capacity of dendritic cells
to promote NKT cell-induced liver injury¨ is published by
professors Hakon Leffler and Ulf Nilsson together with
collaborator professor Miodrag Lukic in Eur. J. Immunol.
A compound discovered by professor Nilsson's and professor
Leffler's group enters phase I clinical trials aiming at a
novel treatment for idiopathic pulmonary fibrosis. The
trials are conducted by Galecto Biotech AB.
October 1, 2013
5th galectins in Lund meeting hosted by professor Thomas
July 17, 2013
The paper ¨Investigation into the Feasibility of
Thioditaloside as a Novel Scaffold for Galectin-3-Specific
Inhibitors¨is published together with collaborator Helen
Blanchard in ChemBioChem.
May 21, 2013
4th galectins in Lund meeting hosted by Derek Logan at the
MAX II laboratory
Three new organic chemists join professor Nilssons group:
Guest professor Dr. Bader Salameh, postdoc Dr. Prahsant
Verma, and PhD student Kristoffer Peterson.
January 8, 2013
3rd galectins in Lund meeting hosted by the laboratory of
professor Stina Oredsson
January 3, 2013
The paper "Tuning the preference of thiodigalactoside- and
lactosamine-based ligands to galectin-3 over galectin-1" is
published in J. Med. Chem.
December 31, 2012
The paper "Galectin-3 deficiency protects pancreatic islet
cells from cytokine-triggered apoptosis in vitro" is
published in J. Cell. Phys.
December 20, 2012
A review chapter "Low molecular weight inhibitors of
galectins" was published in ACS Symposium Series
1115 ""Galectins and Disease - Implications for targeted
September 17-19, 2012
Groups of Leffler and Nilsson made oral presentations at the
symposium " GALECTINS AND GALECTIN THERAPEUTICS" Boston
June 20, 2012
Galectins in Lund web-site launched
May 1, 2012
Studies on ligand-induced self-aggregation of galectin-3
is published in JBC: Ligand Induced Galectin-3
March 17, 2012
Studies on galectin-3 endocytosis is published in Biochim.
Biophys. Acta: Galectin-3 endocytosis by carbohydrate
independent and dependent pathways in different macrophage
like cell types.
February 17, 2012
2nd galectins in Lund meeting in the laboratory of professor
January 13, 2012
1st galectins in Lund meeting in the laboratory of professor
January 12, 2012
Crystallographic work on galectin-7 by collaborator Dr. Ravi
Acharya, University of Bath is published in FEBS J.:
Inhibition mechanism of human galectin-7 by a novel
January 10, 2012
Ultra-high resolution structures of galectin-3 is published
in Biochemistry: The Carbohydrate-Binding Site in
Galectin-3 Is Preorganized To Recognize a Sugarlike
Framework of Oxygens: Ultra-High-Resolution Structures and
December 16, 2011
Work on galectin-3 in hepatitis by collaborator Dr. Miodrag
Lukic, University of Kragujevac, Serbia is accepted by
Hepathology : Galectin-3 Deficiency Prevents
Concanavalin A- Induced Hepatitis in Mice.
November 21, 2011
Work on galectin-1 and 3 in complexes with talosides by
collaborator Dr. Helen Blanchard, Griffith University,
Australia, is accepted by Chemical Biology & Drug
Design: Taloside inhibitors of Galectin-1 and
November 2, 2011
Work on galectin-3 in lung fibrosis by collaborator Dr.
Tariq Sethi, King's Collge, London is accepted by the
Blue journal: Regulation of TGF-β1 driven lung
fibrosis by galectin-3.